Illustration of facial volume loss after rapid weight loss, with one side of the face restored Illustration, not a patient

Ozempic face, restored.

Rapid GLP-1 weight loss can hollow the face. We rebuild it in stages with a physician-led plan built on Juvéderm®, HArmonyCa™, SkinVive™ and Botox Cosmetic®.

Midface VolumeJawlineNeckSkin QualityJuvédermHArmonyCaSkinViveBotox CosmeticCalgaryEdmontonVancouverOkotoksOakvilleMidface VolumeJawlineNeckSkin QualityJuvédermHArmonyCaSkinViveBotox CosmeticCalgaryEdmontonVancouverOkotoksOakville
The Concern

What is Ozempic face, exactly?

61%Report midface volume loss
50%Report skin laxity
35%Report new lines & folds
81%Of clinicians rank HA fillers first

Source: Allergan Aesthetics medical weight-loss research, published by AbbVie in March 2026. Botox Cosmetic’s neck-band indication: Health Canada decision summary, March 2025.

Quick answer: “Ozempic face” is the everyday name for the facial changes that follow rapid weight loss on GLP-1 medications such as semaglutide (Ozempic®, Wegovy®) and tirzepatide (Mounjaro®, Zepbound®). As the body sheds fat, the face loses the pads that give it structure, faster than the skin can shrink to fit. The result is hollowing, deeper folds, looser skin and a face that can read as older or tired even as the body looks healthier.

It is less a side effect of the medication than of the speed and scale of the weight loss. Facial fat sits in distinct compartments: deep pads that prop up the cheeks and temples, and superficial pads that soften the contours. Losing 10 to 15% of body weight in a matter of months deflates both, and skin that stretched over years does not retract in weeks. The same thing happens after bariatric surgery; GLP-1 medications simply made it common.

In Allergan Aesthetics’ 2025 research, 61% of GLP-1 patients reported midface volume loss, 50% skin laxity and 35% new wrinkles or folds. Two thirds said medical weight loss had changed what they wanted from their appearance, and 81% of clinicians named hyaluronic acid fillers as the leading non-surgical answer.

The good news: this is a well-understood anatomy problem with well-understood tools, and the dermatologists and injectors at Rejuvenation treat it every week. See also our guides to facial volume loss and skin laxity.

The Anatomy

What changes, zone by zone.

Weight loss does not deflate the face evenly. These are the nine zones we assess at every GLP-1 consultation, and the Allergan Aesthetics product we reach for in each.

01

Temples

Hollowing above the cheekbones narrows the upper face and makes the brow look heavier than it is.

Juvéderm Voluma
02

Cheeks & midface

Deflated deep fat pads flatten the cheek and let everything below drift downward. The most common complaint, and the first thing we rebuild.

Juvéderm VolumaHArmonyCa
03

Under-eyes

Tear troughs deepen and shadows appear as the cheek beneath them loses support.

Restored via cheek supportDirect treatment assessed individually
04

Nasolabial & marionette folds

Lines from nose to mouth and mouth to chin deepen as the volume above them disappears.

Juvéderm Volift
05

Lips & lip lines

Lips thin and fine vertical lines appear around the mouth.

Juvéderm Volbella
06

Jawline & jowls

Lost support plus looser skin creates jowls and a softer, less defined jaw.

Juvéderm VoluxHArmonyCa
07

Chin & under the chin

A weaker chin profile, and sometimes residual fullness under the chin that the weight loss never cleared.

Juvéderm VoluxBelkyra
08

Neck

Vertical platysma bands and crepey, loose neck skin: the so-called “Ozempic neck.”

Botox CosmeticSkinVive
09

Skin quality overall

Dull, dehydrated, crepey skin across the face that makes every other change look worse.

SkinViveHArmonyCa
Treatment Implementation

One plan, one portfolio.

We build GLP-1 restoration plans on Allergan Aesthetics’ portfolio because the products are designed to work together, are licensed by Health Canada, and let one injector carry you from first support to final refinement without switching systems.

Product
Role in the plan
Where we use it
Typical duration
Deep structural volume that re-props the midface and lifts what sits below it.
Temples, cheeks, midface
Up to 24 months
The firmest gel in the collection, for a sharper jawline and a stronger chin.
Jawline, chin
12 to 18 months
Smooths the folds that deepen once the cheek above them deflates.
Nasolabial folds, marionette lines
12 to 15 months
Soft, subtle volume for lips that have thinned, and for fine lines around the mouth.
Lips, lip lines
Up to 12 months
HArmonyCa™Lift + collagen
A hybrid of hyaluronic acid for immediate lift and calcium hydroxyapatite that stimulates your own collagen over the months that follow.
Cheeks, jawline, lower face
18 to 24 months
Microdroplets of hyaluronic acid placed in the skin itself for hydration, smoothness and glow.
Cheeks, neck, full face
About 6 months
Botox Cosmetic®Neck + expression
Relaxes the vertical neck bands that weight loss exposes and refines the jawline above them; softens frown and forehead lines.
Platysma bands, upper face
3 to 4 months
Belkyra®Under the chin
Dissolves the pocket of fat under the chin that sometimes outlasts the weight loss.
Submental area
Treated fat does not return
Freezes stubborn pockets the weight loss left behind, and rebuilds muscle tone where the body has softened.
Abdomen, flanks, arms, thighs, under the chin
Long-lasting

Durations are typical ranges from Canadian product information and clinical experience; they vary by patient, area and amount used. Products, sequence and amounts are confirmed at your consultation. Rejuvenation also offers Sculptra® and energy-based skin tightening where your physician judges them the better fit.

Timing Matters

Start early. Build in stages.

The instinct is to wait until the weight is off. Current dermatology guidance says the opposite: early, light support preserves structure, and the active weight-loss window is the best time to stimulate collagen while the skin is still retracting. Heavy structural filling waits until your weight settles.

01

Consultation & mapping

Standardized photographs, a review of your medication and weight trajectory, and a zone-by-zone plan with your injector.

Ideally when you start a GLP-1; any time is the right time
02

During active weight loss

Skin quality and collagen first: SkinVive for hydration, HArmonyCa to lift and stimulate collagen as the skin recoils, Botox Cosmetic for neck bands and expression lines. Light Voluma support in the midface if hollowing is advancing quickly.

Months 1 to 9 of weight loss
03

Once your weight stabilizes

Structural restoration with Juvéderm Voluma (temples, cheeks), Volux (jawline, chin), Volift (folds) and Volbella (lips), placed in stages so the result stays proportionate to your new face.

After about 3 to 6 months at a steady weight
04

Refine & maintain

CoolSculpting and CoolTone where pockets or softness remain, Belkyra if fullness under the chin persists, and a maintenance calendar matched to each product’s duration so the result holds.

Ongoing

If skin laxity outpaces what injectables can lift, your physician may add energy-based tightening or discuss surgical options with Rejuvenation Plastic Surgery in Vancouver. Rapid weight loss can also trigger temporary hair shedding; our dermatologists treat that too.

Why Rejuvenation Dermatology

Built for the whole change, not one syringe.

01

Dermatologist-led

GLP-1 weight loss changes skin, hair and face together. A dermatology group assesses all three, and treats the medical changes alongside the cosmetic ones.

02

The full Allergan portfolio under one roof

Juvéderm, HArmonyCa, SkinVive, Botox Cosmetic, Belkyra, CoolSculpting and CoolTone, so your plan never has to be improvised from whatever is in the fridge.

03

Staged and conservative

We replace what you lost, in the order anatomy dictates, and review between sessions. The standard is refreshed, not refilled.

04

Nine clinics, three provinces

Calgary North, South and West, Calgary Vein & Laser, Okotoks, Edmonton Downtown and South, Vancouver Coal Harbour and Oakville, with the same plan and the same products in every one.

05

Honest about limits

Injectables restore volume and improve skin quality; they do not remove a lot of loose skin. When surgery is the better answer, we say so and refer within the Rejuvenation group.

06

A plan that travels with you

Photographs, product records and your maintenance calendar follow you between visits and between clinics, so every injector picks up where the last one left off.

Candidacy

Is this plan right for you?

Most adults who have lost significant weight are candidates for some part of the plan. Your consultation confirms which parts, and in what order.

  • You are losing, or have lost, significant weight on a GLP-1 medication, after bariatric surgery or through lifestyle change
  • Hollowing in the temples, cheeks or under the eyes that was not there before
  • Deeper folds, early jowls or a jawline that has lost its definition
  • Vertical neck bands or crepey, loose neck skin
  • Lips that look thinner than they used to
  • Realistic goals: a face that matches your new body, not a different face
Our Clinics

Ozempic face consultations in Calgary, Edmonton, Vancouver, Okotoks and Oakville.

Nine Rejuvenation Dermatology clinics across Alberta, British Columbia and Ontario, with the same plan and the same Allergan Aesthetics products in every one. Book online, call your clinic directly or get directions.

10201 Southport Rd SW #102
Calgary, AB T2W 4X9

Mon 7am to 7pm · Tue and Wed 7am to 8pm · Thu 7am to 7pm · Fri 7am to 5:30pm · Sat 8am to 3:30pm · Sun 9am to 3pm

130 Country Village Rd NE #405
Calgary, AB T3K 6B8

Mon to Thu 7:30am to 8pm · Fri 7:30am to 5pm · Sat 8am to 3pm · Closed Sun

780 78 Street SW #201
Calgary, AB T3H 3V6

Mon to Thu 7am to 7pm · Fri 7am to 5pm · Closed Sat and Sun

10201 Southport Rd SW #225
Calgary, AB T2W 4X9

Mon to Fri 9am to 5pm · Sat call for hours · Closed Sun

OkotoksAlberta
10 D'Arcy Ranch Dr. #102
Okotoks, AB T1S 5V9

Mon to Fri 9am to 4:30pm · Closed Sat and Sun

10665 Jasper Ave #780
Edmonton, AB T5J 3S9

Mon to Fri 7am to 6pm · Closed Sat and Sun

5083 Windermere Blvd #101
Edmonton, AB T6W 0J5

Mon 7am to 7pm · Tue 7am to 8pm · Wed 7am to 7pm · Thu 7am to 8pm · Fri 7am to 7pm · Sat and Sun 9am to 4pm

Vancouver Coal HarbourBritish Columbia
1055 Canada Pl #62
Vancouver, BC V6C 0C3

Mon to Fri 8am to 4:30pm · Closed Sat and Sun

OakvilleOntario
2295 Bristol Circle #101
Oakville, ON L6H 6P8

Mon to Fri 8am to 5pm · Sat by appointment · Closed Sun

Questions

Frequently asked questions about Ozempic face.

What is Ozempic face?

Ozempic face is the everyday name for the facial changes that follow rapid weight loss on GLP-1 medications such as semaglutide and tirzepatide. As the body sheds fat, the face loses the fat pads that give it structure faster than the skin can shrink to fit, producing hollow temples and cheeks, deeper folds, jowls, thinner lips and loose, crepey skin on the face and neck. The same changes occur after bariatric surgery or any rapid weight loss.

Is Ozempic face permanent?

Lost facial fat does not return unless weight is regained, and skin elasticity recovers only partly, especially after 40. The changes are very treatable, however. Hyaluronic acid fillers restore the support that was lost, collagen-stimulating treatments improve skin firmness over time, and Botox Cosmetic softens neck bands. Most patients see a natural result in stages over a few months.

Should I wait until I have finished losing weight before treating my face?

Not entirely. Current guidance favours starting early with light support: skin quality treatments, collagen stimulation and neuromodulators can begin during active weight loss, when the skin is still retracting. Heavier structural filling of the cheeks, temples and jawline is best done once your weight has been stable for roughly three to six months, so the result stays proportionate to your final face.

Will fillers make my face look heavier or overdone?

No. The goal is to replace the structural support you lost, not to add volume you never had. Treatment is staged and conservative, using products chosen for each zone, and results are reviewed between sessions. Patients consistently describe the result as looking like themselves at their new weight, only rested.

Which Allergan products do you use for Ozempic face, and why?

Juvéderm Voluma for the temples, cheeks and midface; Volux for the jawline and chin; Volift for nasolabial folds and marionette lines; Volbella for the lips and fine lip lines; HArmonyCa for immediate lift with collagen stimulation in the cheeks and lower face; SkinVive for skin hydration and smoothness; Botox Cosmetic for neck bands and expression lines; and Belkyra, CoolSculpting and CoolTone for what the chin and body are left with. They are designed to work together and allow one injector to carry a plan from first support to final refinement.

What about Ozempic neck?

Rapid weight loss often exposes vertical platysma bands and leaves the neck skin crepey. Health Canada authorized Botox Cosmetic for the improvement in the appearance of platysma prominence in March 2025, and it is now a core part of our neck plan, usually alongside SkinVive for skin quality and Volux or HArmonyCa to redefine the jawline above it. Where laxity is advanced, energy-based tightening or a surgical opinion may be recommended.

Does rapid weight loss also cause hair loss?

It can. Telogen effluvium, a temporary shedding, is common after rapid weight loss and usually begins two to four months in. Because Rejuvenation is a dermatology group, the same physicians who manage your facial plan can assess and treat hair shedding.

How long do the results last?

It depends on the product and the area. Structural Juvéderm fillers such as Voluma typically last up to two years, Volux and Volift around a year to eighteen months, Volbella up to a year, HArmonyCa eighteen to twenty-four months, SkinVive about six months and Botox Cosmetic three to four months. A maintenance calendar is built into every plan.

How much does Ozempic face treatment cost?

Plans are quoted per product and per syringe at your consultation, based on the zones being treated. Many patients phase treatment across several visits, which spreads the cost and keeps the result proportionate as the body settles.

I have not started a GLP-1 medication yet. Should I come in first?

Ideally, yes. A baseline set of photographs and a light plan before weight loss begins is the best predictor of a natural result, because we can support the face as it changes rather than rebuild it afterwards.

Begin Here

Book your GLP-1 face consultation.

You did the hard part. Let us help your face catch up. A zone-by-zone assessment of what changed and a staged plan to restore it, before anything is injected. Serving Calgary, Edmonton, Vancouver, Okotoks and Oakville.

Calgary North, South & WestCalgary Vein & LaserOkotoksEdmonton South & DowntownVancouver Coal HarbourOakville

This page is for general information about facial changes associated with weight loss and the treatments offered at Rejuvenation Dermatology. It is not medical advice, and it does not provide information about, recommend or endorse any weight-loss medication. Ozempic® and Wegovy® are registered trademarks of Novo Nordisk A/S; Mounjaro® and Zepbound® are registered trademarks of Eli Lilly and Company; Rejuvenation Dermatology is not affiliated with either company. Juvéderm®, Voluma™, Volux™, Volift™, Volbella™, SkinVive™, HArmonyCa™, Botox Cosmetic®, Belkyra®, CoolSculpting® and CoolTone® are trademarks of Allergan Aesthetics, an AbbVie company. All treatments described are medical procedures with risks as well as benefits; suitability, products, amounts and expected outcomes are determined at a personal consultation with a qualified provider. The hero image on this page is an illustration, not a patient.

Important safety information. Dermal fillers are medical devices licensed by Health Canada. Common side effects include temporary swelling, bruising, tenderness, redness and lumps at the injection site; rare but serious complications, including vascular occlusion, can occur and are why treatment should only be performed by qualified medical professionals. Botox Cosmetic is a prescription medicine; its safety information is on our Botox page. Belkyra can cause swelling, bruising, numbness and, rarely, nerve injury in the treated area. Your injector reviews your health history, medications and previous treatments before any procedure.

Contact Rejuvenation Dermatology

Take the first step toward achieving healthy, radiant, and flawless skin. Contact Rejuvenation Dermatology today to schedule your personalized consultation and explore the advanced treatments tailored to your unique needs.

Learn More About Dermal Fillers and Volume Restoration

The questions behind Ozempic face are the questions behind every filler plan: how much, where, how natural, and how long. Start with our guides.